This city is usually used as a stopping point on the way to Al Jezireh, or further along the Euphrates to Mari and Al Bukamal. It is a major point for engineers and archaeologists; as it is surrounded by excavation sites, where prehistoric artifacts are being recovered and there are a few Oil production plants on newly found oil fields further in Al Jezireh.

Deir Ezzor itself does not have much of a history or any attraction for historical visitors and tourists. However nearby are Doura Europos, Halabiye and Zalabiye, and the excavation site at Mari. 

Deir Ezzor has a museum that concentrates on the prehistoric past of the region, although it does have a section that exhibits other more recent periods.

Deir Ezzor is situated 320 Km south east of Aleppo and 206 Km from Palmyra.